2022 Mercedes-Benz E 350: Recalls, Problems & MPG
Here are the deets on the 2022 Mercedes-Benz E 350: 3 recalls, 8 owner complaints and up to 26 mpg combined.

Recalls
3 vehicle recalls from the manufacturer. Repairs are free. Check your VIN to see if one is still open on your car.
Steering Vehicle recall #22V189000 · 2022 · 8,396 vehicles
What's wrong: Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the active distance assist distronic system.
Why it matters: Deactivated hands-off detection will prevent distronic system features from functioning, including warnings to grab the steering wheel and calling first responders as part of the active emergency stop assist, which can increase the risk of a crash or injury.
The fix: Dealers will update the hand detection control unit software for the distronic system, free of charge. Owner notification letters were mailed May 6, 2022.
Fuel system Vehicle recall #23V445000 · 2023 · 143,551 vehicles
What's wrong: Please refer to mbusa's recall report for specific vehicle details. The fuel pump May shutdown, which can result in a loss of drive power.
Why it matters: A loss of drive power can increase the risk of a crash.
The fix: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024.
Fuel system Vehicle recall #23V880000 · 2023 · 79,676 vehicles
What's wrong: Please refer to mbusa's recall report for specific vehicle details. The fuel pump May shutdown, causing a loss of drive power.
Why it matters: A loss of drive power can increase the risk of a crash.
The fix: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 28, 2024. Owner notification letters will be mailed in phases, on February 23, 2024, April 19, 2024, June 28, 2024, August 9, 2024, October 1, 2024, and December 2, 2024.
Most-reported problems
Owner complaints filed with NHTSA, by component. One complaint can list several components. 0 mention a fire, 0 injuries and 0 deaths were reported.
What owners describe
- Other / unknown (3): no single recurring theme in the descriptions.
- Forward collision avoidance (2): no single recurring theme in the descriptions.
- Fuel system (1): no single recurring theme in the descriptions.
- Electrical (1): no single recurring theme in the descriptions.
The 2022 Mercedes-Benz E 350 has 8 owner complaints, ranking #3 of 7 E 350 model years for complaints (about average; the typical year has 6). Complaints peaked in 2023 (3 filed that year). The typical problem showed up when the car was about 2 years old, at a median of 14,403 miles. Neighboring years: 2021 (13 complaints, 12 recalls), 2023 (6 complaints, 3 recalls).
Engines & fuel economy (EPA)
| Engine | Transmission | Drive | City | Hwy | Comb. | Fuel |
|---|---|---|---|---|---|---|
| 2.0 L 4-cyl turbo | Automatic 9-spd | Rear-Wheel Drive | 23 | 31 | 26 | Premium |
Want the full repair deets? Get the factory manual.
Recall and complaint data tells you what goes wrong. A service manual tells you how to fix it: torque specs, wiring diagrams, fluid capacities and step-by-step procedures for the 2022 Mercedes-Benz E 350.
Closest thing to the factory manual for most years. Pay once, keep it.
Most $25–$78, one-timePro-shop repair procedures, wiring diagrams and TSBs for your exact car.
From $19.99/mo · $39.99/yrOEM procedures, specs and recall/TSB info, the same source many shops use.
From $19.99/mo · $59.99/yrStep-by-step photos written from a real teardown. Great for first-timers.
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FAQ
Does the 2022 Mercedes-Benz E 350 have any recalls?
Yes. NHTSA lists 3 vehicle recalls for the 2022 Mercedes-Benz E 350. Recall repairs are free at any dealer, no matter how old the car is. Check your VIN at nhtsa.gov/recalls.
What are the most common 2022 Mercedes-Benz E 350 problems?
Owners have filed 8 complaints with NHTSA. The most-reported areas are other / unknown (3), forward collision avoidance (2), fuel system (1).
What gas mileage does the 2022 Mercedes-Benz E 350 get?
EPA ratings run up to 26 mpg combined (2.0 L, Automatic 9-spd), across 1 engine and transmission combos.
Where can I get a 2022 Mercedes-Benz E 350 repair manual?
eManualOnline sells downloadable manuals, Mitchell 1 DIY and ALLDATAdiy sell online access to factory repair data, and Haynes sells printed guides and online access. Pick a download if you want to keep it, or a subscription for wiring diagrams and TSBs.